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Looking for any analysis regarding performance of antigen based testing platforms. Has anyone does testing in the field and then validated in a state public health lab (or other trusted laboratory)?
Comments & Events
Brian Erly
We've summarized the data from the FDA on antigen testing, but it's all manufacturer data (using contrived samples and whatnot) for EUAs.
Thanks, Brian ! I would also remind everyone that PPV/NPV is used instead of sensitivity/specificity when the new test is compared to something that is not a gold standard (culture usually is). Since PCR is not a real gold standard, manufactures report PPV/NPV, and thus overestimate test sensitivity/specificity because PCR is very good, but not a perfect test. So, PPV/NPV do not always equal true sensitivity/specificity. George