CSTE National ELR Workgroup

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📈 How are you handling indeterminate or inconclusive results for COVID-19?

Hi all, 

We had been regarding indeterminate or inconclusive results as negative for COVID but just recently received some results on a Cobas RT-PCR test run by some of our major hospitals that indicated that an indeterminate result should be regarded as positive. Was wondering how all of you are handling indeterminate or inconclusive results in general - for PCR/NAAT or for Antigen?

Thank you!

Annie Fine
NYC DOHMH

Comments & Events

Theresa Kittle, Epidemiologist/ELR Coordinator
Hi, Annie,

In Mississippi, we have been handling the indeterminate or inconclusive results the same way as negative results.

Thanks,

Theresa

Theresa S. Kittle, MPH
Epidemiology Program Director
Mississippi State Department of Health
www.HealthyMS.com<http://www.healthyms.com/>
Riki Merrick, Terminologist at APHL
I think it depends why they are calling it inconclusive - in a lot of the PCR tests they use more than one target to identify SARS-CoV-2 and some of the targets are not specific to SARS-CoV-2, but they identify any SArbecovirus - if that is the case, then it may very well be considered positive, as not very many other types will be circulating right now. At CDC/HHS they track detected / not detected and inconclusive and not done as allowable results.
John Satre, Informatician at Iowa Department of Public Health
In Iowa, we treat them as negatives, but our recommendation is to get retested. 
Kristy Lunquest, Maryland Department of Health
We have never treated them as positives in Maryland. The recommendation would also be to get retested.
Sita Smith
Same in MA
Riki Merrick, Terminologist at APHL
I wholeheartedly agree with recommendation to re-test :)
Annie Fine
Thank you all for this useful feedback!  Great group!