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Building the Public Health
            2.  Advanced Molecular Detection Program                              Workforce: AMD Leading the

               CDC has also led advanced molecular detection efforts              Way
               within the agency and continues to support state and               AMD is driven by a modern public health
               local health departments to adopt next generation                  workforce proficient in three unique
               sequencing technologies. The agency’s commitment                   areas: laboratory science, epidemiology,
               to improve the availability of AMD technologies                    and bioinformatics. Bioinformaticians
               has revolutionized public health laboratory and                    are primarily data scientists trained
               epidemiological science to address public health                   to analyze and interpret large data
               threats, including (but not limited to) antibiotic                 sets as applicable to public health. It is
                                                                                  important to recognize the specialized
               resistance, foodborne illnesses, health care                       skill set of bioinformaticians—one not
               associated infections, vaccine preventable diseases,               encompassed by traditional laboratory
               and vector-borne disease. The AMD program’s                        or epidemiology training—which
               successful outcomes include faster and more accurate               includes in-depth computational and
               tests to diagnose infections, improved vaccines,                   statistical analysis, the application of
               identifying emerging pathogens, mapping disease                    bioinformatics to conduct research on
                                                                                  huge molecular data sets such as those
                                                                22
               transmission sooner, and responding to outbreaks.                  generated by AMD technologies, and
               CDC has also recognized the importance of investing                the development of computer tools to
               in the bioinformatics workforce to ensure that                     track patterns of outbreaks. Working
               highly specialized genomic expertise exists in public              together, public health laboratorians,
               health departments. Through a partnership with the                 epidemiologists, and bioinformaticians
               Association of Public Health Laboratories (APHL)                   can harness new technologies to
                                                                                  facilitate more, better, and faster public
               and CSTE, CDC supports bioinformatics training                     health data.
               programs for public health professionals. Through the
               investments and efforts of the AMD program, CDC and                Advancements in technology have
               public health laboratories are now leading laboratory              revolutionized public health laboratory
               innovation to respond to public health threats.                    and epidemiological science by
                                                                                  generating a wealth of data on
            3.  APHL Informatics Messaging Services: A Public Health              the genetic makeup of pathogens.
                                                                                  Traditionally, public health laboratorians
               Information Exchange for Lab Data                                  and epidemiologists have not been
                                                                                  trained in the field of bioinformatics.
               Frustrated by the need for public health laboratories              However, as these advanced laboratory
               to develop and maintain multiple electronic data                   techniques become the norm, public
               exchange connections for every public health partner               health has a growing need for a highly
                                                                                  trained bioinformatics workforce
               that required laboratory data, APHL developed the                  that can maximally leverage these
               APHL Informatics Messaging Services (AIMS) platform                technologies’ benefits. Currently, there
               in 2007. This platform is a secure, interoperable, cloud-          is a large bioinformatics workforce gap
               based data hub that aids in the transport, validation,             in public health that must be addressed.
               translation, and routing of electronic laboratory data,            Two programs—APHL and CDC’s
               eliminating the need for multiple connections. Now,                Bioinformatics Fellowship, which trains
                                                                                  and prepares bioinformaticians to apply
               instead of sending disease and condition-specific data             their expertise within public health, and
               through multiple unique data systems, laboratories                 CDC, CSTE, and APHL’s AMD Academy,
               can link their LIMS to the AIMS platform where their               which trains epidemiologists and public
               critical public health data is automatically routed                health laboratorians in bioinformatics—
               and made available to partners like CDC, hospitals,                must be expanded and replicated.
                                                                                  Investments in fellowships, training
                                                                                  programs, job creation and professional
            22 Advanced Molecular Detection. cdc.gov. https://www.cdc.gov/amd/pdf/amd-at-a-glance-final-508.pdf.  development must be prioritized for
                                                                                  public health to leverage and stay ahead
                                                                                  of advances in technology.

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