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bioinformatics use high performance computing methods to analyze vast quantities of genetic data.
            When epidemiologists investigate foodborne outbreaks, they can now leverage AMD to quickly link
            genetically related clusters of illness to contaminated food.  AMD is replacing the less accurate PulseNet
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            technology developed in the 1990s for foodborne outbreak detection and response. However, like PulseNet
            data, AMD data cannot not stand on its own. It still needs to be linked to other epidemiological data such
            as case interviews and environmental tests in order to pinpoint the cause or source of the outbreak and
            implement optimal control measures. A comprehensive public health response will require interoperable
            data systems between the public health laboratory and epidemiologists.

            Follow the Data

            While the exchange of data from local and state public health laboratories to federal agencies has been
            well established, substantive limitations in overall data exchange during foodborne outbreaks still exist.
            In addition to sending data to federal agencies, the public health laboratory must also share that data
            with epidemiologists in their local jurisdictions. Food exposure information, which is necessary to link
            disease clusters to the contaminated food source, is collected in the field through case interviews and
            requires data exchange between epidemiologists, laboratories, and federal agencies. Although some
            public health laboratories have set up electronic systems to exchange foodborne data to epidemiologists,
            this is not widespread. Public health laboratories still rely heavily on time-consuming manual data entry
            into spreadsheets, phone calls, faxes and emails. In some instances, an epidemiologist will drive to the
            public health laboratory twice per week to physically pick up lab reports and bring them back to the
            health department for manual data entry. As a result, real-time data are not exchanged, creating a traffic
            jam of information. Anecdotes from the field have also highlighted situations where the quickest way to
            share outbreak-related data was to email a cell phone photo of a computer screen because the software
            and system between the sender and receiver
            were not interoperable, and thus incapable of
            data exchange. When time is of the essence                        In some instances, an
            in a foodborne outbreak for both preventing
            further illness and not adversely impacting or      epidemiologist will drive to the
            implicating the wrong industry, these methods         public health laboratory twice
            delay responses and leave important health
            information vulnerable to human error such            per week to physically pick up
            as inaccurate transcription, keying errors,
            duplicated or incomplete data entry, or no         lab reports and bring them back
            information.                                            to the health department for

            Measles Resurgence                                                      manual data entry.


            The nation is in the midst of a massive measles
            resurgence and cases are at the highest since
            the United States eliminated the disease in 2000. A vaccine-preventable disease, measles is a highly
            contagious infection that causes high fever, coughing, conjunctivitis, and rashes. Complications can range
            from mild to severe, including ear infections, pneumonia, encephalitis, and death. Since one infected
            person can spread the disease through coughing and sneezing to 90 percent of unvaccinated people
            around them—even two hours after leaving a room or defined air space—a timely and swift public health
            response to a measles outbreak is critical.


            15  Advanced Molecular Detection: An In-Depth Look. cdc.gov. https://www.cdc.gov/amd/pdf/amd-indepth-look-P.pdf..



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